Call Natural Bio Health at 512-501-1016 for a complimentary consultation and learn how natural (bio identical) progesterone can help decrease the risk of breast cancer, protect against osteoporosis, moderate PMS symptoms, improve the quality of sleep, reduce or eliminate headaches, improve libido and reduce the risk of Alzheimer’s disease.

The following are just a few of the many studies illustrating the beneficial effects of natural (not synthetic) progesterone:

Breast Cancer Incidence in Women With a History of Progesterone Deficiency, American Journal of Epidemiology, 1981, Vol. 114, No.2.Study followed women treated for infertility for several years to compare their risks of developing breast cancer. The study reported that women with endogenous progesterone deficiency had 5.4 times the risk of breast cancer compared to women without progesterone deficiency. It also noted that women in the progesterone deficiency group experiences a 10-fold increase in deaths from all malignant neoplasms compared to the non progesterone deficiency group.

What Your Doctor May Not Tell You About Breast Cancer, John R. Lee, M.D., 2002

Excerpts from Book:

“…., progesterone is an important factor in the prevention and treatment of breast cancer.” (at page 172)

“In breast tissue, estrogen stimulates breast duct cells to proliferate, whereas progesterone inhibits this proliferation and causes maturation and differentiation of the cells making them more resistant to cancerous changes.” (at page 189)

“Estrogen dominance is the cause of fibrocystic breasts, and topical progesterone is the preferable treatment.” (at page 189).

“There can be little doubt that progesterone protects against estrogen induced breast cancer.” (at page 191)

Formby, B. and T.S. Wiley, “Progesterone Inhibits Growth and Induces Apoptosis in Breast Cancer Cells: Inverse Effects on Bcl-2 and p53. Ann Clin Lab Sci 28 (1998): 360-369. Study reported that estrogen added to breast cancer cells cultures activate the oncogene (cancer causing gene) Bcl-2, whereas progesterone activates the cancer-protective gene p53.

Hrushesky, W.J., “Menstrual Cycle Timing of Breast Cancer Resection: Prospective Study is Overdue.” J. Natl Cancer Inst. , 87(2)(1995):143-4. Outlined seven known metabolic mechanisms by progesterone protects against breast cancer.

"Mastering The Protocols for Bio Identical Hormone Replacement Therapy". Neal Rouzier, M.D., Revised 03/07: “Progesterone protects against breast cancer.”

Progestins [synthetic progesterone] and progesterone in hormone replacement therapy and risk of breast cancer. J. Steroid Biochem Mol Biol. 2005 May 20, Campagnoli C. “Controlled studies and most observational studies published over the last 5 years suggest that the addition of synthetic progestins to estrogen in hormone replacement therapy [e.g like provera] …. increase the risk of breast cancer risk compared to estrogen alone. By contrast, a recent study suggests that the addition of natural progesterone in cyclic regimens does not affect breast cancer risk. This finding is consistent with invivo data suggesting that progesterone does not have a detrimental effect on breast tissue.” …

Menopausal Hormone Replacment Therapy With Continuous Daily Oral Micronized Estradiol and Progesterone. Obstetrics & Gynecology, Joel Hargrove, M.D. 0029-78-44/89/53.50. “All women on E2 and progesterone had a decrease in total cholesterol and an increase in high-density lipoprotein cholesterol from baseline. Those on conjugated estrogens and emdroxyprogesterone acetate [synthetic progestins) has no significant change from baseline in total cholesterol.”

The Safe and Effective Alternative to Provera, NATURAL PROGESTERONE,
Gail Valentine, D.O. LIFE Enhancement, October 1997, Issue 38. “Women who replace their missing estrogen and progesterone using natural versions of these hormones (natural HRT) can reap all of the benefits of conventional HRT with few or none of its unwanted effects or risks.” “Nature harnesses estrogen’s carcinogenic potential by “opposing” it with progesterone…. Women who take “unopposed” estrogen may have a risk of endometrial cancer as much as 14% higher.”

Million Women Study (as cited by Kenna Stephenson, M.D., F.A.A.F.P., Associate Professor of Family Medicine, Author of “Awakening Athena, in “The Rise and Fall of HRT.” Study followed 1.084 million women aged 50-64 from 1996 to 2001 in UK and concluded: Synthetic estrogens (CEE) increases breast cancer risk RR=1.3. Progestins (synthetic) (including low dose MPA) (synthetics) when added to estrogens (synthetics) additionally increased breast cancer risk RR=2.0. Breast cancer risk increase with duration of the therapy (synthetics).

The Hormone Restoration Model in the Clinical Care of Women, Stephenson, K., MD. Noted that endogenous progesterone has “Anti-estrogenic effects in breast, brain, endometrium.” Also referenced were: “Progesterone and Breast Cancer Risk, Plu-Bureau G et.al. Cancer Detection and Prevention, 1992, 23(4),290-296 “cohort study of 1150 French women showed no increase breast cancer risk with topical progesterone” and Progesterone and Breast Cancer Risk in the E3N Cohort Study: “Risk of breast cancer associated with estrogens plus micronized progesterone (natural) was RR 0.9 [less than 1]; while the risk for estrogen alone was RR1.1 and the risk for estrogen plus synthetic progestins was RR1.4.” Int J Cancer, 2005:114:448-454.