Benefits of DHEA Supplementation:
- Improves function of the immune system
- Improves brain function
- Hinders the damage that stress can cause
- Increases energy
- Reduces body fat and cholesterol, thereby preventing heart disease
- Increases insulin sensitivity
- Potent antioxidant by preventing formation of free radicals
- Improves mood
- Cognitive enhancement
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Hormones – DHEA (Dehydroepiandrosterone)
DHEA is a steroid hormone produced naturally in the adrenal glands, gonads and brain. Clinical studies have shown that DHEA has a profound effect on the immune system, sex drive, metabolism and emotional stability.
Its effect on the immune system via the modulation of stress hormones and its use as a powerful antioxidant, demonstrate potent age-resisting capabilities. Other health related benefits include the ability to alter cognitive decline, to help the body cope with stress, and to exert a healthy influence over the heart via cholesterol modulation.
Most of the tremendous effects seen from DHEA are based on its ability to stimulate protein synthesis from the cell which in turn results in an increase in cell regeneration, increase in protein synthesis, and an improvement of immune function which forestalls disease processes. DHEA is the ultimate antioxidant as it appears to prevent the formation of free radicals.
The mean concentration of DHEA in serum decreases progressively from a peak at age 25 to less than twenty percent (20%) of that peak before the age of 70. Serum levels are typically low in those with chronic diseases, such as cancer and AIDS, and heart disease as well.
Possible Side Effects:
In very high doses various androgenic effects including acne, deepening of the voice, hirsutism and hair loss have been reported in women using supplemental DHEA.
DHEA is usually taken orally in the capsule form; however creams/gels are also effective. DHEA can be obtained over the counter or through a compounding pharmacy. Pharmacies that compound DHEA will micronize and slow release it for a more consistent serum level. Hormones obtained through a pharmacy are usually of a higher pharmaceutical grade then that obtained over the counter.
Frequently Asked Questions:
If I develop acne what should I do?
Stop taking until the acne clears then resume at a lower dose.
I don’t feel any different after taking the DHEA, is that normal?
Some people do not notice a difference taking DHEA. Some do notice increased energy and improved brain function. As long as your doctor is replacing the proper dosage it is a very good hormone to take daily.
DHEA has been shown to increase insulin sensitivity which means that less insulin is required. This results in protection against diabetes and greater control for those who have diabetes. It has also been shown to have significant effect in treating connective tissue disorders such as lupus, a disease that tends to show minimal improvement from standard therapy.
Insulin-resistance has lead to over 14,000,000 Americans having some form of diabetes. Insulin-resistance or inability of insulin to do its job results in increased glucose, increased weight, obesity, and heart disease. DHEA has now been discovered to be the missing link between insulin-resistance and atherosclerosis. It is the decline in DHEA that precipitates the insulin-resistance that can lead to damage of the cardiovascular system. Diabetics given DHEA have noted marked decrease insulin resistance that prevents the harmful effects of insulin on the vasculature.
The Journal of Clinical Endocrinology and Metabolism in 1995 stated that there are over 2500 published papers documenting DHEA’s multiple benefits. This important paper documented that we produce half of the DHEA at age 40 than we did when we were 20.
Some elderly people produce no DHEA whatsoever. DHEA was shown to improve the quality of life and postpone many of the unpleasant effects of aging such as fatigue and muscle weakness. Patients receiving DHEA slept better, had more energy, and were better equipped to handle stress compared with a placebo group not receiving DHEA. Other potential benefits of DHEA include immune enhancement, anti-cancer effects, anti-atherosclerotic effects, anti-depression, life extension and cognitive enhancement.
DHEA is available over-the-counter and is common in drug stores, warehouse stores, and health food stores. Unfortunately, many of the over-the-counter products from foreign countries contain contaminants and therefore are not entirely pure pharmaceutical grade.
The half life of DHEA from over-the-counter sources is approximately six hours, which would require that one take the supplement three times a day. Natural Bio Health will prescribe DHEA in a sustained release micronized form which allows for complete absorption as well as a sustained level over a 24-hour time period, thereby foregoing the need to take the supplement three times a day.
In addition, Natural Bio Health will prescribe only pure pharmaceutical grade DHEA that is compounded by a pharmacy to assure a 100% pure pharmaceutical compound.
“DHEA administration reduces abdominal fat, decreases insulin resistance and protects against metabolic syndrome and diabetes.” JAMA 2004 November; Vol.292(18):2233-2247.
“Low DHEA levels are associated with depression and depressed mood.” J American Gerentology Soc.1999 June;47(6):685-91.
“DHEA is beneficial in treatment of major depression in women.” Am. J Psychiatry 1999 April;156(4):646-649.
“DHEA improves mood and fatigue.” J Psych 2000 Dec;85(12):4650-56.
“DHEA improves well being, sexuality, and cognition”. Endocrinology Research. 2000 Nov;26(4):505
“DHEA improves immune function and decreases mortality.” Critical Care Med. 2001Feb;29(2):380